Description

5-Fluoro-4-Methylpyridine-3-Carboxylic Acid is a high-value fluorinated pyridine derivative, a crucial building block in modern synthetic chemistry. Its core value lies in its ability to introduce both fluorine and a carboxylic acid functional group into complex molecular architectures, enabling the fine-tuning of physicochemical properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs), especially in kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides where the fluorine atom enhances biological activity and metabolic stability.
• Ligand Synthesis: Serves as a precursor for creating complex chelating ligands used in catalysis and material science.
• Material Science: Employed in the synthesis of functionalized polymers and advanced organic electronic materials.
• Chemical Biology: Useful as a probe or labeling agent due to the reactive carboxylic acid group and the spectroscopic handle provided by the fluorine atom.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	5-Fluoro-4-Methylpyridine-3-Carboxylic Acid
CAS No.	1211584-22-3
Molecular Formula	C7H6FNO2
Molecular Weight	155.13 g/mol
Synonyms	3-Pyridinecarboxylic acid, 5-fluoro-4-methyl-; 4-Methyl-5-fluoropyridine-3-carboxylic acid; 5-Fluoro-4-methylnicotinic acid; 5-Fluoro-4-methyl-3-pyridinecarboxylic acid; 1211584-22-3; 5-Fluoro-4-methyl-pyridine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 5-Fluoro-4-Methylpyridine-3-Carboxylic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.