Description

2-Fluoro-3-Methylisonicotinaldehyde is a high-purity fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic introduction of both fluorine and an aldehyde functional group onto the pyridine scaffold, enabling precise molecular modifications. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, especially in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in catalysis and material science applications.
• Fluorinated Building Block: Employed in medicinal and combinatorial chemistry for the introduction of the 2-fluoro-3-methylpyridine moiety into more complex molecular architectures.
• Chemical Research & Development: Utilized in academic and industrial R&D settings for exploring new synthetic pathways and creating proprietary chemical libraries.

Basic Information

Product Name	2-Fluoro-3-Methylisonicotinaldehyde
CAS No.	1211581-05-3
Molecular Formula	C8H6FNO
Molecular Weight	151.14 g/mol
Synonyms	2-Fluoro-3-methylpyridine-4-carboxaldehyde; 3-Methyl-2-fluoropyridine-4-carbaldehyde; 4-Formyl-2-fluoro-3-methylpyridine; 2-Fluoro-3-methylisonicotinic aldehyde; 2-Fluoro-3-methyl-4-pyridinecarboxaldehyde; 2-Fluoro-3-methyl-4-formylpyridine; Isonicotinaldehyde, 2-fluoro-3-methyl-
EINECS	Contact for details

Quality Control

Our 2-Fluoro-3-Methylisonicotinaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This material is easily oxidized; for long-term storage, consider under an inert atmosphere such as nitrogen or argon. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.