Description

3-Chloro-5-(Trifluoromethyl)Pyridine-2-Sulfonyl Chloride is a high-value, multi-functional chemical intermediate characterized by its reactive sulfonyl chloride and halogenated pyridine structure. This compound matters for its critical role as a key building block in the synthesis of advanced agrochemicals and pharmaceuticals, enabling the introduction of the sulfonamide pharmacophore. It is primarily needed by R&D chemists and process development scientists in the agrochemical, pharmaceutical, and specialty chemical industries for creating novel active ingredients and functional materials. The product, with CAS number 1211578-91-4, is supplied to meet the stringent purity and consistency requirements of modern organic synthesis.

Application

• Agrochemical Intermediate: A pivotal precursor for the synthesis of modern sulfonylurea and sulfonamide herbicides and fungicides, contributing to crop protection solutions.
• Pharmaceutical Building Block: Used in medicinal chemistry for the development of drug candidates, particularly those targeting enzymes where a sulfonamide group is essential for binding.
• Chemical Synthesis Reagent: Serves as a versatile reactant for introducing the 2-chlorosulfonyl moiety onto complex molecules in research and scale-up processes.
• Material Science Applications: Potential use in the synthesis of functional polymers and advanced materials that require specific halogenated and sulfonated aromatic units.

Basic Information

Item	Detail
Product Name	3-Chloro-5-(Trifluoromethyl)Pyridine-2-Sulfonyl Chloride
CAS No.	1211578-91-4
Molecular Formula	C7H2Cl2F3NO2S
Molecular Weight	304.06 g/mol
Synonyms	2-Pyridinesulfonyl chloride, 3-chloro-5-(trifluoromethyl)-; 3-Chloro-5-trifluoromethylpyridine-2-sulfonyl chloride; 2-Chlorosulfonyl-3-chloro-5-(trifluoromethyl)pyridine; 1211578-91-4; 3-Chloro-5-(trifluoromethyl)-2-pyridinesulfonyl chloride
EINECS	Contact for details

Quality Control

Our 3-Chloro-5-(Trifluoromethyl)Pyridine-2-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.