Description

5-Fluoro-2-Methoxy-Pyridin-3-Ylamine is a high-purity, advanced pharmaceutical intermediate characterized by its pyridine core with strategic fluorine and methoxy substitutions. This compound matters as a critical building block for medicinal chemists, enabling the synthesis of novel active pharmaceutical ingredients (APIs) with potentially enhanced metabolic stability and target binding affinity. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating new drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug molecules, particularly in oncology, CNS, and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the fluorine atom can improve biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Chemical Research: Employed in academic and industrial R&D for structure-activity relationship (SAR) studies and library synthesis for high-throughput screening.
• Fine Chemical Production: Utilized in the multi-step synthesis of complex, high-value specialty chemicals and dyes.

Basic Information

Product Name	5-Fluoro-2-Methoxy-Pyridin-3-Ylamine
CAS No.	1211541-93-3
Molecular Formula	C6H7FN2O
Molecular Weight	142.13 g/mol
Synonyms	3-Amino-5-fluoro-2-methoxypyridine; 5-Fluoro-2-methoxy-3-pyridinamine; 2-Methoxy-5-fluoropyridin-3-amine; 3-Pyridinamine, 5-fluoro-2-methoxy-; 5-Fluoro-2-methoxypyridin-3-amine; 1211541-93-3; 5-Fluoro-2-methoxy-3-aminopyridine
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-Methoxy-Pyridin-3-Ylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Any single unknown impurity	≤0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.