Description

6-Bromo-3-Fluoro-2-Methoxypyridine is a high-purity, multi-functional halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. Its value lies in the strategic positioning of bromine and fluorine atoms on the methoxypyridine scaffold, enabling precise molecular modifications for creating complex target molecules. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality intermediates for drug discovery and specialty chemical development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders, oncology, and anti-infective therapies.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where the fluorine and bromine substituents can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for constructing sophisticated nitrogen-containing ligands used in transition metal catalysis for asymmetric synthesis.
• Material Science Research: Employed in the creation of organic electronic materials, such as charge-transport layers or components for organic light-emitting diodes (OLEDs), due to its electron-deficient pyridine core.
• Chemical Biology Probe Synthesis: Utilized to build molecular probes for studying enzyme function and biological pathways, leveraging its potential for further functionalization.

Basic Information

Product Name	6-Bromo-3-Fluoro-2-Methoxypyridine
CAS No.	1211529-85-9
Molecular Formula	C6H5BrFNO
Molecular Weight	206.01 g/mol
Synonyms	2-Methoxy-6-bromo-3-fluoropyridine; 3-Fluoro-6-bromo-2-methoxypyridine; 6-Bromo-3-fluoro-2-pyridinol methyl ether; 2-Bromo-5-fluoro-6-methoxypyridine; 3-Fluoro-2-methoxy-6-bromopyridine; Pyridine, 6-bromo-3-fluoro-2-methoxy-; 1211529-85-9
EINECS	Contact for details

Quality Control

Our 6-Bromo-3-Fluoro-2-Methoxypyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.