Description

2-Amino-1-(5-(Trifluoromethyl)Pyridin-2-Yl)Ethanone CAS NO 1211529-78-0 is a high-value trifluoromethylpyridine derivative, serving as a critical building block in modern synthetic chemistry. Its core value lies in the strategic combination of a reactive amino ketone moiety with a stable, electron-deficient pyridine ring, enabling the synthesis of complex, functionalized molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group improves metabolic stability and bioavailability.
• Ligand & Catalyst Development: Serves as a versatile scaffold for creating novel chelating ligands and organocatalysts used in asymmetric synthesis and metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials that require specific nitrogen-containing heterocycles.
• Chemical Biology Probes: Utilized as a building block for fluorescent tags, photoaffinity labels, and other molecular probes to study biological systems.

Basic Information

Product Name	2-Amino-1-(5-(Trifluoromethyl)Pyridin-2-Yl)Ethanone
CAS No.	1211529-78-0
Molecular Formula	C8H7F3N2O
Molecular Weight	204.15 g/mol
Synonyms	2-Amino-1-[5-(trifluoromethyl)-2-pyridinyl]ethanone; 1-(5-(Trifluoromethyl)pyridin-2-yl)-2-aminoethanone; 2-Amino-1-(5-trifluoromethylpyridin-2-yl)ethanone; 2-Pyridineethanone, 2-amino-1-[5-(trifluoromethyl)-2-pyridinyl]-; 2'-Amino-5'-(trifluoromethyl)acetophenone (pyridine analog); α-Amino-5-(trifluoromethyl)picolyl ketone
EINECS	Contact for details

Quality Control

Our 2-Amino-1-(5-(Trifluoromethyl)Pyridin-2-Yl)Ethanone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance in cGMP and ISO 9001 environments for pharmaceutical and fine chemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.