Description

Methyl 5-Bromo-6-Chloro-3-Fluoropicolinate is a high-purity, multi-halogenated picolinate ester serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in providing a versatile, functionalized scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality building blocks for complex synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Chemical Research & Development: Serves as a versatile precursor for further functionalization (e.g., hydrolysis, cross-coupling reactions) in academic and industrial R&D labs.
• Material Science Precursor: Potential use in the synthesis of specialized ligands, metal-organic frameworks (MOFs), or functional polymers.

Basic Information

Product Name	Methyl 5-Bromo-6-Chloro-3-Fluoropicolinate
CAS No.	1211528-83-4
Molecular Formula	C7H4BrClFNO2
Molecular Weight	268.47 g/mol
Synonyms	Methyl 5-bromo-6-chloro-3-fluoropyridine-2-carboxylate; 5-Bromo-6-chloro-3-fluoro-2-pyridinecarboxylic acid methyl ester; 2-Pyridinecarboxylic acid, 5-bromo-6-chloro-3-fluoro-, methyl ester; Methyl 5-bromo-6-chloro-3-fluoropicolinate; 5-Bromo-6-chloro-3-fluoropicolinic acid methyl ester
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized and controlled using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to confirm identity, purity, and consistency. Certificates of Analysis (COA) are available upon request, providing full transparency on all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.