Description

5-Methoxy-2-(Trifluoromethyl)Pyridine-4-Carboxylic Acid is a high-value, multi-functional pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique trifluoromethyl and methoxy substitution pattern makes it an essential intermediate for creating novel compounds with enhanced biological activity and physicochemical properties. This product is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group can improve metabolic stability and lipophilicity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of advanced organic materials, including liquid crystals and electronic chemicals, due to its aromatic core and functional handles.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	5-Methoxy-2-(Trifluoromethyl)Pyridine-4-Carboxylic Acid
CAS No.	1211525-32-4
Molecular Formula	C8H6F3NO3
Molecular Weight	221.13 g/mol
Synonyms	4-Pyridinecarboxylic acid, 5-methoxy-2-(trifluoromethyl)-; 5-Methoxy-2-(trifluoromethyl)isonicotinic acid; 2-Trifluoromethyl-5-methoxypyridine-4-carboxylic acid; 5-Methoxy-2-trifluoromethylpyridine-4-carboxylic acid; 1211525-32-4; 5-Methoxy-2-(trifluoromethyl)-4-pyridinecarboxylic acid
EINECS	Contact for details

Quality Control

Our production of 5-Methoxy-2-(Trifluoromethyl)Pyridine-4-Carboxylic Acid adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system is designed to meet the exacting standards required for pharmaceutical and agrochemical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The product may be hygroscopic; keep the container tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.