Description

3-Bromo-2-Methoxy-4-(Trifluoromethyl)Pyridine is a high-value, multi-functional heterocyclic building block essential for advanced chemical synthesis. Its unique structure, featuring bromine, methoxy, and trifluoromethyl substituents on the pyridine ring, makes it a critical intermediate for introducing specific functionalities into target molecules. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting central nervous system (CNS) disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for creating specialized ligands, catalysts, and functional monomers used in advanced polymers and electronic materials.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Negishi, Stille) to form complex biaryl structures.
• Fluorine Chemistry: The stable trifluoromethyl group is valuable for modulating lipophilicity, metabolic stability, and bioavailability in medicinal chemistry and agrochemical design.

Basic Information

Item	Details
Product Name	3-Bromo-2-Methoxy-4-(Trifluoromethyl)Pyridine
CAS No.	1211521-34-4
Molecular Formula	C8H5BrF3NO
Molecular Weight	256.03 g/mol
Synonyms	3-Bromo-2-methoxy-4-(trifluoromethyl)pyridine; 2-Methoxy-3-bromo-4-trifluoromethylpyridine; 4-(Trifluoromethyl)-3-bromo-2-methoxypyridine; Pyridine, 3-bromo-2-methoxy-4-(trifluoromethyl)-; 1211521-34-4
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-2-Methoxy-4-(Trifluoromethyl)Pyridine is produced and tested under a strict quality management system. We guarantee high-purity material suitable for demanding research and scale-up applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to ensure full traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.