Description

(3-Chloro-4-Fluorophenyl)Methanesulfonyl Chloride is a high-purity, multi-functional chemical intermediate essential for advanced organic synthesis. Its value lies in its dual reactive sites, the sulfonyl chloride and the halogenated aromatic ring, which enable precise molecular construction. This compound is critically needed by R&D and production teams in the pharmaceutical and agrochemical industries for developing new active ingredients, particularly in the synthesis of sulfonamide-based molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel sulfonamide drugs, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and pesticides with enhanced efficacy and selectivity.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and functional materials.
• Chemical Biology Probes: Employed in the design and synthesis of activity-based probes for studying protein function and interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring the introduction of a (3-chloro-4-fluorophenyl)methanesulfonyl moiety.

Basic Information

Product Name	(3-Chloro-4-Fluorophenyl)Methanesulfonyl Chloride
CAS No.	1211516-98-1
Molecular Formula	C7H5Cl2FO2S
Molecular Weight	243.08 g/mol
Synonyms	1-Chloro-2-fluoro-4-(chlorosulfonylmethyl)benzene; 4-Chloro-3-fluorobenzylsulfonyl chloride; (3-Chloro-4-fluorobenzyl)sulfonyl chloride; 3-Chloro-4-fluorobenzenemethanesulfonyl chloride; 4-(Chlorosulfonylmethyl)-1-chloro-2-fluorobenzene; α-Chlorosulfonyl-3-chloro-4-fluorotoluene
EINECS	Contact for details

Quality Control

Our (3-Chloro-4-Fluorophenyl)Methanesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.