Description

4-Bromo-5-(Trifluoromethyl)Picolinic Acid is a high-value, multi-functional heterocyclic building block. This compound is critical for the synthesis of advanced agrochemicals and pharmaceuticals due to its unique combination of bromine and trifluoromethyl substituents on the pyridine core. It is primarily sought after by R&D chemists and process development scientists in the agrochemical, pharmaceutical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Agrochemical Intermediate: A key synthon for developing next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the trifluoromethyl group.
• Pharmaceutical Building Block: Used in medicinal chemistry for the synthesis of drug candidates, particularly in areas targeting enzyme inhibition where the picolinic acid scaffold is relevant.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands in catalysis and coordination chemistry.
• Material Science Research: Employed in the development of advanced organic materials, including liquid crystals and organic semiconductors.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke synthetic routes and scale-up projects.

Basic Information

Product Name	4-Bromo-5-(Trifluoromethyl)Picolinic Acid
CAS No.	1211516-48-1
Molecular Formula	C7H3BrF3NO2
Molecular Weight	269.99 g/mol
Synonyms	4-Bromo-5-(trifluoromethyl)pyridine-2-carboxylic acid; 2-Pyridinecarboxylic acid, 4-bromo-5-(trifluoromethyl)-; 4-Bromo-5-trifluoromethylpicolinic acid; 4-Bromo-5-trifluoromethyl-2-pyridinecarboxylic acid; 1211516-48-1; 4-Br-5-CF3-Picolinic Acid
EINECS	Contact for details

Quality Control

Our 4-Bromo-5-(Trifluoromethyl)Picolinic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere if necessary and opened with minimal exposure to ambient humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.