Description

4-Pyridinecarboxylic Acid, 2-Fluoro-5-Hydroxy- is a high-value fluorinated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both a carboxylic acid and a hydroxyl group on a fluorinated pyridine ring, makes it an essential intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used to develop novel herbicides and pesticides with enhanced efficacy and environmental profiles.
• Ligand Synthesis: Serves as a starting material for creating complex chelating agents and catalysts in coordination chemistry.
• Material Science: Building block for advanced polymers and liquid crystals where fluorine substitution imparts specific stability and electronic properties.
• Chemical Biology Probes: Utilized in the design of molecular probes and fluorescent tags for biochemical research.

Basic Information

Product Name	4-Pyridinecarboxylic Acid, 2-Fluoro-5-Hydroxy-
CAS No.	1211515-83-1
Molecular Formula	C6H4FNO3
Molecular Weight	157.10 g/mol
Synonyms	2-Fluoro-5-hydroxypyridine-4-carboxylic acid; 5-Hydroxy-2-fluoropyridine-4-carboxylic acid; 2-Fluoro-5-hydroxyisonicotinic acid; 4-Carboxy-2-fluoro-5-hydroxypyridine; 2-Fluoro-5-hydroxy-4-pyridinecarboxylic acid; 2-Fluoro-5-hydroxypicolinic acid; 2-Fluoro-5-hydroxy-4-picolinic acid
EINECS	Contact for details

Quality Control

Our 4-Pyridinecarboxylic Acid, 2-Fluoro-5-Hydroxy- is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality management system is designed to support cGMP-compliant applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.