Description

3-Pyridinol, 2,4-Difluoro- is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring fluorine atoms at the 2 and 4 positions of the pyridine ring, makes it an essential intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated drug candidates, particularly for central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Used to construct novel herbicides, fungicides, and insecticides where the fluorine atoms enhance biological activity and metabolic stability.
• Ligand & Catalyst Development: Serves as a versatile scaffold for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Building block for developing advanced organic electronic materials, such as fluorinated semiconductors or liquid crystals.
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for studying biological systems due to its fluorine NMR handle.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects.

Basic Information

Product Name	3-Pyridinol, 2,4-Difluoro-
CAS No.	1211515-53-5
Molecular Formula	C5H3F2NO
Molecular Weight	131.08 g/mol
Synonyms	2,4-Difluoropyridin-3-ol; 2,4-Difluoro-3-hydroxypyridine; 3-Hydroxy-2,4-difluoropyridine; 2,4-Difluoro-3-pyridinol; 3-Pyridinol, 2,4-difluoro-; 2,4-Difluoropyridine-3-ol
EINECS	Contact for details

Quality Control

Every batch of 2,4-Difluoropyridin-3-ol is produced and tested under strict quality management protocols. We provide comprehensive analytical data to ensure the material meets the high-purity requirements for research and process development. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profile as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound should be kept under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.