Description

5-Chloro-6-Fluoronicotinaldehyde is a high-value, multi-functional chemical building block characterized by its reactive aldehyde group and halogen-substituted pyridine ring. This compound is essential for the synthesis of complex molecules, offering a strategic point for further functionalization in advanced chemical processes. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and anti-infective agents.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its halogenated nicotinaldehyde structure.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic electronic materials and functional polymers due to its electron-deficient aromatic system.
• Custom Synthesis and Contract Manufacturing: A critical raw material for fine chemical and CDMO (Contract Development and Manufacturing Organization) companies producing bespoke intermediates for clients.

Basic Information

Product Name	5-Chloro-6-Fluoronicotinaldehyde
CAS No.	1211515-52-4
Molecular Formula	C6H3ClFNO
Molecular Weight	159.55 g/mol
Synonyms	5-Chloro-6-fluoropyridine-3-carbaldehyde; 3-Formyl-5-chloro-6-fluoropyridine; 5-Chloro-6-fluoro-3-pyridinecarboxaldehyde; 6-Fluoro-5-chloronicotinaldehyde; 5-Chloro-6-fluoro-3-formylpyridine; 5-Chloro-6-fluoronicotinaldehyde; 3-Pyridinecarboxaldehyde, 5-chloro-6-fluoro-
EINECS	Contact for details

Quality Control

Our 5-Chloro-6-Fluoronicotinaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized (store under inert atmosphere) and light-sensitive (store away from light). Keep away from strong oxidizing agents, strong bases, and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.