Description

2-Bromo-3-(Difluoromethyl)Pyridine, 97% is a high-purity halogenated pyridine derivative, a crucial building block in modern synthetic chemistry. Its value lies in the strategic placement of bromine and difluoromethyl groups on the pyridine ring, enabling precise molecular construction and the introduction of fluorine's beneficial properties. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, where it serves as a key intermediate for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A versatile synthon for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of next-generation pesticides and herbicides, where the difluoromethyl group can enhance metabolic stability and bioavailability.
• Material Science Research: Serves as a precursor for creating specialized ligands, functionalized polymers, or advanced organic electronic materials.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tags for studying biological systems.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) to form complex biaryl structures.

Basic Information

Product Name	2-Bromo-3-(Difluoromethyl)Pyridine, 97%
CAS No.	1211515-00-2
Molecular Formula	C7H5BrF2N
Molecular Weight	222.02 g/mol
Synonyms	3-(Difluoromethyl)-2-bromopyridine; 2-Bromo-3-difluoromethylpyridine; Pyridine, 2-bromo-3-(difluoromethyl)-; 1211515-00-2; 2-Bromo-3-(difluoromethyl)pyridine
EINECS	Contact for details

Quality Control

Our 2-Bromo-3-(Difluoromethyl)Pyridine is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure the 97% minimum purity and identity are met. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to guarantee traceability and consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.