Description

6-Methylpyridine-3-Sulfonyl Chloride Hydrochloride is a high-purity, reactive sulfonyl chloride derivative used as a critical building block in advanced organic synthesis. This compound is essential for introducing the 6-methylpyridine-3-sulfonyl moiety, a key functional group in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. It is primarily utilized by research and development chemists and process scale-up teams in the pharmaceutical, agrochemical, and fine chemical industries seeking reliable, high-quality intermediates for complex molecule construction.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in the development of kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used to construct sulfonamide-based herbicides, fungicides, and plant growth regulators with specific biological activity.
• Chemical Biology & Proteomics: Serves as a reactive handle for labeling proteins or modifying biomolecules in research applications.
• Material Science Research: Employed in the creation of functionalized polymers and advanced materials with tailored surface properties.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing complex organic molecules for clients.

Basic Information

Product Name	6-Methylpyridine-3-Sulfonyl Chloride Hydrochloride
CAS No.	1210868-11-3
Molecular Formula	C6H7Cl2NO2S
Molecular Weight	228.10 g/mol
Synonyms	3-Pyridinesulfonyl chloride, 6-methyl-, hydrochloride (1:1); 6-Methyl-3-pyridinesulfonyl chloride hydrochloride; 6-Methylpyridine-3-sulfonyl chloride HCl; 2-Methyl-5-sulfonylchloridopyridinium chloride; 6-Methylnicotinic sulfonyl chloride hydrochloride; 2-Methyl-5-chlorosulfonylpyridinium chloride
EINECS	Contact for details

Quality Control

Our 6-Methylpyridine-3-Sulfonyl Chloride Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and titration methods, to ensure high chemical purity and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.