Description

8-Fluoroquinoline-6-Boronic Acid is a high-value, multi-functional organoboron building block essential for modern synthetic chemistry. Its core value lies in enabling efficient carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone methodology for constructing complex molecules. This compound is critically needed by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for the development of novel active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing fluorinated quinolone derivatives and other active pharmaceutical ingredients (APIs) with potential therapeutic applications.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced bioactivity and stability.
• Material Science Research: Serves as a precursor for creating novel organic electronic materials, ligands for catalysts, and fluorescent probes.
• Cross-Coupling Reactions: Primarily employed in palladium-catalyzed Suzuki-Miyaura cross-coupling to introduce the quinoline scaffold into more complex molecular architectures.
• Chemical Biology & Medicinal Chemistry: Utilized in fragment-based drug discovery and the synthesis of chemical probes for target identification and validation.
• Academic & R&D Laboratories: A versatile reagent for methodological development and the synthesis of novel heterocyclic compounds in research settings.

Basic Information

Item	Detail
Product Name	8-Fluoroquinoline-6-Boronic Acid
CAS No.	1210048-29-5
Molecular Formula	C9H7BBrFNO2
Molecular Weight	255.87 g/mol
Synonyms	6-Borono-8-fluoroquinoline; (8-Fluoroquinolin-6-yl)boronic Acid; 8-Fluoro-6-quinolineboronic Acid; 8-Fluoroquinoline-6-boronic Acid Pinacol Ester (precursor); B-(8-Fluoro-6-quinolinyl)boronic Acid; 1210048-29-5; 8-Fluoro-6-quinolylboronic Acid
EINECS	Contact for details

Quality Control

Our 8-Fluoroquinoline-6-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and elemental analysis, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, it is recommended to handle the material under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to minimize exposure to moisture. Recommended storage temperature: 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥95% (Typical 97-99%)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.