Description

2,3-Difluoroisonicotinonitrile is a high-value, fluorinated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine atoms and a nitrile group on the pyridine ring, makes it an indispensable intermediate for creating novel compounds with tailored properties. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new agrochemicals, pharmaceuticals, and functional materials. Its precise reactivity profile enables the synthesis of complex molecules for high-growth applications.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used to develop novel herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Ligand Synthesis: Building block for creating specialized ligands used in catalysis and material science.
• Functional Material Development: Intermediate in the production of advanced polymers, liquid crystals, and electronic materials.
• Chemical Biology Probes: Utilized in the design of molecular probes for studying biological systems and disease mechanisms.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research labs for custom synthesis projects and process development.

Basic Information

Product Name	2,3-Difluoroisonicotinonitrile
CAS No.	1210041-67-0
Molecular Formula	C6H2F2N2
Molecular Weight	140.09 g/mol
Synonyms	2,3-Difluoropyridine-4-carbonitrile; 4-Cyano-2,3-difluoropyridine; 2,3-Difluoro-4-pyridinecarbonitrile; Isonicotinonitrile, 2,3-difluoro-; Pyridine-4-carbonitrile, 2,3-difluoro-; 1210041-67-0; 2,3-Difluoropyridin-4-yl cyanide
EINECS	Contact for details

Quality Control

Our 2,3-Difluoroisonicotinonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as identity, assay, and impurity profiles. We adhere to relevant industry standards and can support development projects requiring material for research, pilot, or commercial scale.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.