Description

2-Fluoromethylpyridine-6-Carboxylic Acid Methyl Ester is a high-value fluorinated pyridine derivative, a crucial building block in advanced organic synthesis. Its core value proposition lies in its unique molecular architecture, which enables the precise introduction of fluorine and ester functionalities into complex target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, especially in medicinal chemistry programs targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluoromethyl and ester groups contribute to enhanced biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic electronic materials.
• Fluorine Chemistry Research: An important reagent for studying structure-activity relationships (SAR) and introducing fluorine atoms into heterocyclic systems.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring specific fluoropyridine motifs.

Basic Information

Item	Detail
Product Name	2-Fluoromethylpyridine-6-Carboxylic Acid Methyl Ester
CAS No.	1209248-98-5
Molecular Formula	C9H8FNO2
Molecular Weight	181.16 g/mol
Synonyms	Methyl 2-(fluoromethyl)pyridine-6-carboxylate; 6-(Methoxycarbonyl)-2-pyridinemethanol, 2-fluoro-; 2-Fluoromethyl-6-pyridinecarboxylic acid methyl ester; Methyl 2-(fluoromethyl)-6-pyridinecarboxylate; 2-(Fluoromethyl)pyridine-6-carboxylic acid methyl ester; 6-Carbomethoxy-2-fluoromethylpyridine
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoromethylpyridine-6-Carboxylic Acid Methyl Ester is produced and tested under a strict quality management system. We guarantee high-purity material suitable for demanding research and scale-up applications. Comprehensive analytical testing, including HPLC, GC, NMR, and MS, is performed to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. Store away from incompatible materials such as strong bases and fluorides.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.