Description

(S)-1-(5-Fluoropyridin-2-Yl)Ethanamine Dihydrochloride is a high-purity chiral amine salt, serving as a critical building block in advanced organic synthesis. Its value lies in providing a defined stereocenter and enhanced solubility for the development of targeted bioactive molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for creating novel active pharmaceutical ingredients (APIs) and crop protection agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, especially for central nervous system (CNS) and oncology targets.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where specific stereochemistry is required for optimal activity.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Research: Employed in the design and synthesis of molecular probes and tool compounds for studying biological pathways.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring a fluorinated pyridyl-ethylamine scaffold with high enantiomeric purity.

Basic Information

Product Name	(S)-1-(5-Fluoropyridin-2-Yl)Ethanamine Dihydrochloride
CAS No.	1208893-73-5
Molecular Formula	C7H10F N2 • 2HCl
Molecular Weight	225.09 g/mol
Synonyms	(S)-1-(5-Fluoropyridin-2-yl)ethan-1-amine dihydrochloride; (S)-1-(5-Fluoro-2-pyridinyl)ethylamine dihydrochloride; (S)-α-Methyl-5-fluoropyridine-2-methanamine dihydrochloride; (S)-5-Fluoro-2-(1-aminoethyl)pyridine dihydrochloride; (S)-2-(1-Aminoethyl)-5-fluoropyridine dihydrochloride; (S)-1-(5-Fluoro-2-pyridyl)ethylamine dihydrochloride; (S)-5-Fluoropyridin-2-ylethanamine dihydrochloride
EINECS	Contact for details

Quality Control

Our (S)-1-(5-Fluoropyridin-2-Yl)Ethanamine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure it meets the high-purity standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.