Description

5-Fluoro-6-Methylpyridin-2-Yl-2-Boronic Acid CAS NO 1208101-45-4 is a high-purity boronic acid derivative, a crucial building block in modern synthetic organic chemistry. Its primary value lies in its role as a key intermediate in cross-coupling reactions, enabling the efficient construction of complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A critical precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in kinase inhibitor and CNS-active compound research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as those used in OLEDs and organic semiconductors.
• Chemical Biology Probes: Utilized to create tagged molecules and bioconjugates for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A vital raw material for CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	5-Fluoro-6-Methylpyridin-2-Yl-2-Boronic Acid
CAS No.	1208101-45-4
Molecular Formula	C7H9BFNO2
Molecular Weight	168.96 g/mol
Synonyms	(5-Fluoro-6-methylpyridin-2-yl)boronic acid; 2-Borono-5-fluoro-6-methylpyridine; 5-Fluoro-6-methyl-2-pyridineboronic acid; 5-Fluoro-6-methylpyridine-2-boronic acid; 2-(5-Fluoro-6-methyl-2-pyridinyl)boronic acid; Boronic acid, B-(5-fluoro-6-methyl-2-pyridinyl)-
EINECS	Contact for details

Quality Control

Our 5-Fluoro-6-Methylpyridin-2-Yl-2-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Anhydrous Basis)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.