Description

6-Chloro-2,3-Difluorobenzenesulfonylchloride is a high-purity, multi-functional sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its dual reactive sites, enabling the efficient introduction of the sulfonyl group and facilitating further functionalization for creating complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Building block for novel herbicides, fungicides, and insecticides that require the specific 2,3-difluoro-6-chloro substitution pattern.
• Material Science: Used in the development of specialty polymers, liquid crystals, and advanced electronic materials.
• Chemical Research: A versatile reagent for constructing complex heterocycles and for use in cross-coupling reactions and nucleophilic substitutions.
• Dye & Pigment Industry: Intermediate in the production of specialized colorants and fluorescent markers.

Basic Information

Product Name	6-Chloro-2,3-Difluorobenzenesulfonylchloride
CAS No.	1208078-24-3
Molecular Formula	C6H2Cl2F2O2S
Molecular Weight	247.05 g/mol
Synonyms	2,3-Difluoro-6-chlorobenzenesulfonyl chloride; 1-Chloro-2,3-difluoro-6-(chlorosulfonyl)benzene; 6-Chloro-2,3-difluorobenzene-1-sulfonyl chloride; Benzenesulfonyl chloride, 6-chloro-2,3-difluoro-; 2,3-Difluoro-6-chlorophenylsulfonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 6-Chloro-2,3-Difluorobenzenesulfonylchloride is produced and tested under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, and NMR to ensure identity, purity, and consistency meet the exacting standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.