Description

1-Bromo-2-Chloro-3,6-Difluorobenzene is a high-purity, multi-substituted aromatic halogenated compound that serves as a critical building block in advanced organic synthesis. Its precise halogen and fluorine substitution pattern makes it a valuable intermediate for creating complex molecules with tailored electronic and steric properties. This compound is primarily sought after by researchers and manufacturers in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the difluoro motif can enhance bioavailability and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for creating fluorinated aromatic cores essential in electronic display technologies and organic light-emitting diodes (OLEDs).
• Polymer Chemistry: Employed as a monomer or cross-linking agent in the production of specialty polymers with high thermal stability and chemical resistance.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new coupling reactions and constructing complex polycyclic aromatic systems.
• Material Science: Used in the synthesis of ligands for catalysts and in the creation of advanced organic frameworks for sensing or separation applications.

Basic Information

Product Name	1-Bromo-2-Chloro-3,6-Difluorobenzene
CAS No.	1208077-34-2
Molecular Formula	C6H2BrClF2
Molecular Weight	227.44 g/mol
Synonyms	2-Bromo-1-Chloro-3,6-Difluorobenzene; 3,6-Difluoro-1-Bromo-2-Chlorobenzene; 1-Bromo-2-Chloro-3,6-Difluorobenzol; Benzene, 1-bromo-2-chloro-3,6-difluoro-; 2-Chloro-1-bromo-3,6-difluorobenzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-2-Chloro-3,6-Difluorobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.