Description

1-Bromo-2-Chloro-5,6-Difluorobenzene is a high-purity, multi-halogenated benzene derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique substitution pattern, which allows for selective functionalization and the introduction of halogen atoms into complex molecular architectures. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing halogenated aromatic systems for enhanced bioactivity and metabolic stability.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides, where the difluoro and chloro/bromo groups contribute to binding affinity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated aromatic cores in electronic materials, contributing to improved charge transport, thermal stability, and optical properties.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to introduce functionalized aryl groups into target molecules.
• Polymer & Material Science: Acts as a monomer or modifier for creating high-performance polymers with specific halogen-related properties like flame retardancy or chemical resistance.

Basic Information

Product Name	1-Bromo-2-Chloro-5,6-Difluorobenzene
CAS No.	1208077-25-1
Molecular Formula	C6H2BrClF2
Molecular Weight	227.44 g/mol
Synonyms	2-Bromo-1-Chloro-4,5-Difluorobenzene; 5,6-Difluoro-1-Bromo-2-Chlorobenzene; 1-Bromo-2-Chloro-5,6-Difluorobenzol; Benzene, 1-bromo-2-chloro-5,6-difluoro-; 2-Chloro-1-bromo-4,5-difluorobenzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-2-Chloro-5,6-Difluorobenzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting key parameters such as assay and impurity profiles. Our quality commitment supports applications requiring GMP-grade starting materials and compliance with global regulatory standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.