Description

4-Bromo-5-Chloro-2-Fluorobenzene-1-Sulfonyl Chloride is a high-purity, multi-functional aromatic sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique halogenated pattern, which provides distinct reactivity and selectivity for constructing complex molecular architectures. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it is used to introduce sulfonamide or sulfonate functionalities into target molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for sulfonamide-based drugs targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and functional materials.
• Chemical Biology Probes: Utilized to create activity-based probes or affinity labels for studying enzyme function and protein interactions.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.
• Dye & Pigment Intermediate: Employed in the synthesis of complex dyes and organic pigments due to its robust aromatic core.

Basic Information

Product Name	4-Bromo-5-Chloro-2-Fluorobenzene-1-Sulfonyl Chloride
CAS No.	1208075-41-5
Molecular Formula	C6H2BrCl2FO2S
Molecular Weight	312.40 g/mol
Synonyms	1-Bromo-2-chloro-4-fluoro-5-sulfonylchloridebenzene; 2-Fluoro-4-bromo-5-chlorobenzenesulfonyl chloride; 4-Bromo-5-chloro-2-fluorobenzenesulfonyl chloride; Benzenesulfonyl chloride, 4-bromo-5-chloro-2-fluoro-; 5-Chloro-4-bromo-2-fluorobenzenesulfonyl chloride
EINECS	Contact for details

Quality Control

Our 4-Bromo-5-Chloro-2-Fluorobenzene-1-Sulfonyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.