Description

4-Iodo-2,6-Difluorotoluene is a high-purity halogenated aromatic building block of significant importance in advanced organic synthesis. Its unique structure, featuring iodine and fluorine substituents on a toluene backbone, makes it a versatile intermediate for constructing complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting fluorine-containing drug candidates.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and pesticides, where the difluorotoluene moiety can enhance biological activity and stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for creating advanced organic electronic materials, including liquid crystals and charge-transport layers for OLED displays.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to form biaryl and other complex structures.
• Fluorine Chemistry Research: An essential reagent for academic and industrial research exploring the effects of fluorine substitution on molecular properties and reactivity.
• Ligand & Catalyst Development: Utilized in the synthesis of specialized ligands and organocatalysts used in asymmetric synthesis and other catalytic processes.

Basic Information

Item	Detail
Product Name	4-Iodo-2,6-Difluorotoluene
CAS No.	1208074-97-8
Molecular Formula	C7H5F2I
Molecular Weight	253.92 g/mol
Synonyms	1-Iodo-3,5-difluoro-4-methylbenzene; 2,6-Difluoro-4-iodotoluene; 4-Methyl-3,5-difluoroiodobenzene; Toluene, 4-iodo-2,6-difluoro-; 3,5-Difluoro-4-iodotoluene; 4-Iodo-2,6-difluoromethylbenzene
EINECS	Contact for details

Quality Control

Our 4-Iodo-2,6-Difluorotoluene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures material consistency and reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.