Description

2,3-Difluoro-6-Methoxybenzenesulfonylchloride is a high-value, multi-functional chemical intermediate prized for its reactive sulfonyl chloride group and strategically placed fluorine atoms. Its primary value lies in enabling the synthesis of complex sulfonamide derivatives, which are critical scaffolds in modern pharmaceutical and agrochemical discovery. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries seeking to introduce sulfonamide functionality into novel molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of sulfonamide-based drugs targeting various diseases.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides where the sulfonamide moiety enhances biological activity and selectivity.
• Material Science Research: Serves as a precursor for functionalized polymers and specialty chemicals with tailored surface properties.
• Chemical Biology & Proteomics: Employed as a reactive handle for bioconjugation and the development of chemical probes to study protein function.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses serving the life sciences sector.
• Dye & Pigment Intermediate: Potential use in the synthesis of specialized sulfonated dyes and colorants.

Basic Information

Product Name	2,3-Difluoro-6-Methoxybenzenesulfonylchloride
CAS No.	1208074-96-7
Molecular Formula	C7H5ClF2O3S
Molecular Weight	242.63 g/mol
Synonyms	2,3-Difluoro-6-methoxybenzenesulfonyl chloride; 2,3-Difluoro-6-methoxybenzene-1-sulfonyl chloride; 1-(Chlorosulfonyl)-2,3-difluoro-6-methoxybenzene; 6-Methoxy-2,3-difluorobenzenesulfonyl chloride; Benzenesulfonyl chloride, 2,3-difluoro-6-methoxy-; 2,3-Difluoroanisole-6-sulfonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 2,3-Difluoro-6-Methoxybenzenesulfonylchloride is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and other relevant techniques is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.