Description

1-Chloro-3,4-Difluoro-2-Iodobenzene is a high-value, multi-halogenated aromatic building block essential for advanced organic synthesis. Its unique substitution pattern makes it a critical intermediate for constructing complex molecules with precise electronic and steric properties. This compound is primarily sought after by researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially in fluorinated drug candidates.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the difluoro and iodo groups can enhance biological activity.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as semiconductors and liquid crystals, where halogenated aromatics tune material properties.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags for imaging and diagnostic applications due to the reactive iodine handle.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	1-Chloro-3,4-Difluoro-2-Iodobenzene
CAS No.	1208074-94-5
Molecular Formula	C6H2ClF2I
Molecular Weight	274.44 g/mol
Synonyms	2-Chloro-1,2-difluoro-3-iodobenzene; 3,4-Difluoro-2-iodo-1-chlorobenzene; 1-Chloro-3,4-difluoro-2-iodobenzene; Benzene, 1-chloro-3,4-difluoro-2-iodo-; 2-Iodo-3,4-difluorochlorobenzene
EINECS	Contact for details

Quality Control

Our 1-Chloro-3,4-Difluoro-2-Iodobenzene is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.