Description

2-Chloro-3,6-Difluorobenzenesulfonylchloride is a high-purity, multi-functional sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its dual reactive sites, enabling the efficient introduction of the sulfonyl group and facilitating further functionalization for complex molecule construction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used to construct novel herbicides, fungicides, and insecticides by incorporating the sulfonyl moiety into active molecules.
• Material Science: Building block for creating specialized polymers, dyes, and liquid crystals with tailored properties.
• Chemical Research: A versatile reagent for academic and industrial R&D in organic and medicinal chemistry.
• Cross-Coupling Reactions: Serves as an electrophile in palladium-catalyzed coupling reactions to form carbon-sulfur bonds.

Basic Information

Product Name	2-Chloro-3,6-Difluorobenzenesulfonylchloride
CAS No.	1208074-71-8
Molecular Formula	C6H2Cl2F2O2S
Molecular Weight	247.05 g/mol
Synonyms	2-Chloro-3,6-difluorobenzenesulfonyl chloride; 1-Chloro-2,5-difluoro-4-(chlorosulfonyl)benzene; Benzenesulfonyl chloride, 2-chloro-3,6-difluoro-; 2,5-Difluoro-3-chlorobenzenesulfonyl chloride; 3,6-Difluoro-2-chlorobenzenesulfonyl chloride; 4-Chlorosulfonyl-1,2-difluoro-5-chlorobenzene
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-3,6-Difluorobenzenesulfonylchloride is produced and tested under a strict quality management system. We ensure high purity and batch-to-batch consistency through advanced analytical techniques including HPLC, GC, and NMR. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases, oxidizers, and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.