Description

2-Fluoro-4-Iodo-6-Methoxypyridine is a high-purity, multi-functional halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it an exceptionally valuable scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. This compound is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for its versatility in cross-coupling reactions and as a precursor for further functionalization.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, leveraging its halogen atoms for structural diversity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as components for OLEDs or conductive polymers, due to the electron-withdrawing nature of the halogens.
• Cross-Coupling Reactions: The iodine and fluorine substituents make it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form complex biaryl structures.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological systems and diagnostic applications.

Basic Information

Product Name	2-Fluoro-4-Iodo-6-Methoxypyridine
CAS No.	1207840-36-5
Molecular Formula	C6H5FINO
Molecular Weight	253.01 g/mol
Synonyms	4-Iodo-2-fluoro-6-methoxypyridine; 6-Methoxy-2-fluoro-4-iodopyridine; 2-Fluoro-6-methoxy-4-iodopyridine; Pyridine, 2-fluoro-4-iodo-6-methoxy-; 1207840-36-5; 4-Iodo-2-fluoro-6-methoxypyridine; 2-Fluoro-4-iodo-6-methoxypyridine
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-4-Iodo-6-Methoxypyridine is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards and customer specifications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.