Description

2-(Trichloromethyl)-6-Fluoropyridine is a high-value halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both a reactive trichloromethyl group and a fluorine substituent, makes it an indispensable intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting CNS and anti-infective agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and metabolic stability.
• Chemical Research: Serves as a versatile precursor in academic and industrial laboratories for exploring new reactions and synthesizing complex heterocyclic compounds.
• Material Science: Potential building block for creating specialty polymers and functional materials with specific electronic or surface properties.
• Ligand and Catalyst Development: Utilized in the synthesis of novel ligands for metal catalysis and organocatalysis.

Basic Information

Product Name	2-(Trichloromethyl)-6-Fluoropyridine
CAS No.	1207664-71-8
Molecular Formula	C6H3Cl3FN
Molecular Weight	214.45 g/mol
Synonyms	6-Fluoro-2-(trichloromethyl)pyridine; 2-(Trichloromethyl)-6-fluoropyridine; 6-Fluoro-α,α,α-trichloro-2-picoline; 2-Pyridinecarbonyl trichloride, 6-fluoro-; 6-Fluoro-2-trichloromethylpyridine; α,α,α-Trichloro-6-fluoro-2-picoline
EINECS	Contact for details

Quality Control

Every batch of 2-(Trichloromethyl)-6-Fluoropyridine is manufactured and tested under strict quality management protocols to ensure consistency and reliability for your critical syntheses. We provide comprehensive analytical data, including HPLC purity, identity confirmation (IR, NMR), and impurity profiling. A Certificate of Analysis (COA) is supplied with each shipment, detailing all relevant specifications. Our quality systems are designed to support cGMP and ISO standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.