Description

Nudifloramide-D3 CAS NO 1207384-48-2 is a deuterium-labeled isotopologue of Nudifloramide, a compound of significant interest in pharmaceutical and biochemical research. This stable isotope-labeled analog is essential for use as an internal standard in quantitative mass spectrometry, ensuring high accuracy and reliability in analytical measurements. It is primarily utilized by researchers and developers in the fields of drug metabolism and pharmacokinetics (DMPK), bioanalytical chemistry, and the development of novel therapeutic agents.

Application

• Internal Standard for LC-MS/MS: Critical for precise quantification of the parent compound in complex biological matrices like plasma, serum, and tissue homogenates.
• Drug Metabolism Studies (DMPK): Enables accurate tracking of drug absorption, distribution, metabolism, and excretion (ADME) in preclinical and clinical research.
• Bioanalytical Method Development: Used to validate and optimize sensitive and specific analytical methods in compliance with regulatory guidelines (e.g., FDA, EMA).
• Pharmacokinetic/Pharmacodynamic (PK/PD) Modeling: Provides reliable data for modeling drug concentration-time profiles and effect relationships.
• Isotope Dilution Mass Spectrometry (IDMS): Serves as a spike-in standard for high-precision measurements, minimizing matrix effects and instrument variability.
• Reference Material for Certified Standards: Acts as a key component in the preparation of certified reference materials (CRMs) for quality control laboratories.

Basic Information

Product Name	Nudifloramide-D3
CAS No.	1207384-48-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Nudifloramide-d3; Deuterated Nudifloramide; [²H₃]-Nudifloramide; Nudifloramide (D3 labeled); Nudifloramide Internal Standard; Nudifloramide Stable Isotope; Nudifloramide-D₃; CAS 1207384-48-2
EINECS	Contact for details

Quality Control

Our Nudifloramide-D3 is manufactured under strict quality systems to ensure the high chemical purity and isotopic enrichment required for sensitive analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as assay by HPLC, isotopic purity by mass spectrometry, and chemical purity. We adhere to relevant industry standards for research chemicals, and our quality commitment ensures reliable and reproducible performance in your critical studies.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed under inert atmosphere if specified and kept in a low-humidity environment. For long-term stability, consider storage at -20°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Assay (HPLC)	≥ 98.0%
Isotopic Purity (D3)	≥ 98.0 atom % D
Chemical Purity	≥ 95.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.