Description

3-(Trifluoromethoxy)-2-Pyridinemethanamine is a specialized pyridine derivative featuring a trifluoromethoxy substituent and an aminomethyl functional group, making it a valuable building block in advanced organic synthesis. This compound is critical for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique fluorine-containing scaffold can impart enhanced metabolic stability and bioavailability. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used to develop advanced herbicides, fungicides, and insecticides where the trifluoromethoxy group enhances biological activity and environmental persistence.
• Ligand & Catalyst Development: Serves as a starting material for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Building block for synthesizing functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for studying biological systems and enzyme mechanisms.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	3-(Trifluoromethoxy)-2-Pyridinemethanamine
CAS No.	1206977-79-8
Molecular Formula	C7H7F3N2O
Molecular Weight	192.14 g/mol
Synonyms	2-(Aminomethyl)-3-(trifluoromethoxy)pyridine; [3-(Trifluoromethoxy)pyridin-2-yl]methanamine; 3-(Trifluoromethoxy)-2-pyridylmethylamine; 2-Pyridinemethanamine, 3-(trifluoromethoxy)-; α-Amino-3-(trifluoromethoxy)-2-picoline
EINECS	Contact for details

Quality Control

Our 3-(Trifluoromethoxy)-2-Pyridinemethanamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing identity, purity, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.