Description

3-Iodo-6-(Trifluoromethyl)Pyridin-2-Ol is a high-value, halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. Its unique structure, combining iodine and a trifluoromethyl group on the pyridine core, makes it an indispensable intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and anti-infective therapies.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand & Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and other catalytic processes.
• Material Science Research: Employed in the creation of organic electronic materials, such as charge-transport layers or fluorinated molecular components for OLEDs and semiconductors.
• Chemical Biology Probes: Useful for constructing molecular probes and tags for imaging and diagnostic applications due to the reactivity of the iodine moiety.
• Custom Synthesis & Contract Manufacturing: A vital building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	3-Iodo-6-(Trifluoromethyl)Pyridin-2-Ol
CAS No.	1206597-55-8
Molecular Formula	C6H3F3INO
Molecular Weight	288.99 g/mol
Synonyms	2-Hydroxy-3-iodo-6-(trifluoromethyl)pyridine; 3-Iodo-6-(trifluoromethyl)-2-pyridinol; 3-Iodo-6-(trifluoromethyl)-2(1H)-pyridinone; 6-(Trifluoromethyl)-3-iodopyridin-2-ol; 3-Iodo-2-hydroxy-6-trifluoromethylpyridine; 2-Pyridinol, 3-iodo-6-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Every batch of 3-Iodo-6-(Trifluoromethyl)Pyridin-2-Ol is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and scale-up activities. A detailed Certificate of Analysis (COA) is supplied with each shipment, typically including results for identity, purity (HPLC), and specified impurities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.