Description

Glpg0634 is a high-purity, non-peptidic small molecule compound identified by the CAS number 1206101-20-3. This compound is of significant interest in pharmaceutical research and development, particularly as a potential therapeutic agent. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery and preclinical studies. The material is characterized by its specific molecular structure, making it a valuable candidate for investigating novel biological pathways.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or active pharmaceutical ingredient (API) in the discovery and development of new therapeutic drugs.
• Preclinical Studies: Used in in vitro and in vivo studies to evaluate pharmacokinetics, pharmacodynamics, and initial efficacy.
• Biochemical Assays: Employed as a reference standard or inhibitor in high-throughput screening and target validation assays.
• Chemical Synthesis: Acts as a sophisticated building block for the synthesis of more complex molecules and analogs in medicinal chemistry.
• Academic Research: Utilized in university and institutional labs for fundamental research into specific biological mechanisms and disease models.

Basic Information

Product Name	Glpg0634
CAS No.	1206101-20-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	GLPG-0634; GLPG0634; 1206101-20-3; Filgotinib; GS-6034; 2-[(3S,4R)-3-Ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-1-piperidinyl]-2-oxo-N-(2,2,2-trifluoroethyl)acetamide; JNJ-40346527; (3S,4R)-3-Ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)-2-oxo-1-piperidineacetamide
EINECS	Contact for details

Quality Control

Our Glpg0634 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with agreed specifications. We support development activities with materials suitable for research use and can discuss GMP-grade production for advanced clinical stages.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator to prevent degradation. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.