Description

1-Benzyl-4-[n-(1-Propanoyl)-n-Phenylamino]-4-Methoxymethylpiperidine-D3 is a deuterated piperidine derivative, a high-value intermediate or reference standard in advanced chemical synthesis. This compound is critical for pharmaceutical research and development, particularly in the creation of deuterium-labeled drug candidates to study metabolic pathways and enhance pharmacokinetic properties. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate stable isotope labels into complex molecules.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of deuterated active pharmaceutical ingredients (APIs) for drug discovery and development.
• Metabolic Studies: Used as an internal standard or tracer in mass spectrometry-based assays to investigate drug metabolism and pharmacokinetics (DMPK).
• Isotope Labeling: Essential for the preparation of compounds where specific hydrogen atoms are replaced with deuterium to alter and study chemical and biological properties.
• Chemical Reference Standard: Provides a certified material for analytical method development, validation, and quality control in GMP/GLP environments.
• Medicinal Chemistry Research: Enables structure-activity relationship (SAR) studies by probing the effects of deuterium incorporation on biological activity.
• Agrochemical Development: Potential use in creating labeled analogs of agrochemicals for environmental fate and residue analysis studies.

Basic Information

Product Name	1-Benzyl-4-[n-(1-Propanoyl)-n-Phenylamino]-4-Methoxymethylpiperidine-D3
CAS No.	1204688-15-2
Molecular Formula	C23H28D3N2O2
Molecular Weight	~364.53 g/mol
Synonyms	1-Benzyl-4-[N-(1-oxopropyl)-N-phenylamino]-4-(methoxymethyl)piperidine-d3; 4-(Methoxymethyl)-1-benzyl-4-[N-(1-oxopropyl)-N-phenylamino]piperidine-d3; Deuterated 1-Benzyl-4-(N-propanoyl-N-phenylamino)-4-methoxymethylpiperidine; [D3]-1-Benzyl-4-[N-(1-propanoyl)-N-phenylamino]-4-methoxymethylpiperidine
EINECS	Contact for details

Quality Control

Our 1-Benzyl-4-[n-(1-Propanoyl)-n-Phenylamino]-4-Methoxymethylpiperidine-D3 is manufactured under strict quality control protocols to ensure high chemical and isotopic purity, essential for research and development applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing specifications for identity, purity (by HPLC/NMR), deuterium enrichment, and related substances. We adhere to relevant industry standards and can support development toward cGMP-grade material upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Deuterium Enrichment (NMR/MS)	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.