Description

1-(1,1-Difluoroethyl)-3-Methylbenzene is a specialized fluorinated aromatic compound, serving as a high-value building block in advanced organic synthesis. Its core value lies in the introduction of a difluoroethyl group, which can significantly alter the metabolic stability, lipophilicity, and binding affinity of target molecules. This compound is essential for R&D and production chemists in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting improved pharmacokinetic properties.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated organic electronic materials for displays and lighting applications.
• Organic Synthesis Building Block: A versatile reagent for introducing fluorinated motifs in complex molecule construction for various fine chemical applications.
• Positron Emission Tomography (PET) Tracer Development: Potential use as a precursor for fluorine-18 labeled radiopharmaceuticals used in medical imaging.

Basic Information

Item	Details
Product Name	1-(1,1-Difluoroethyl)-3-Methylbenzene
CAS No.	1204295-94-2
Molecular Formula	C9H10F2
Molecular Weight	156.17 g/mol
Synonyms	3-Methyl-α,α-difluoroethylbenzene; 1-(1,1-Difluoroethyl)-3-methylbenzene; m-Methyl-α,α-difluoroethylbenzene; (1,1-Difluoroethyl)-3-methylbenzene; 3-Methyl-1-(1,1-difluoroethyl)benzene; Benzene, 1-(1,1-difluoroethyl)-3-methyl-; α,α-Difluoro-m-xylene (related); Difluoroethyltoluene
EINECS	Contact for details

Quality Control

Our 1-(1,1-Difluoroethyl)-3-Methylbenzene is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC/HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is 2-8°C for long-term stability. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.