Description

(1,1-Difluoro-2-Methylpropyl)-Benzene is a specialized fluorinated aromatic building block of significant interest in advanced organic synthesis. Its unique structure, featuring a gem-difluoro group adjacent to a tertiary carbon, makes it a valuable precursor for introducing lipophilic and metabolically stable motifs into target molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, particularly those requiring fluorinated aromatic or heterocyclic scaffolds to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the difluoromethyl group can enhance biological activity and environmental persistence.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the development of specialty polymers and advanced materials with tailored surface properties.
• Ligand and Catalyst Development: Employed in organometallic chemistry for the synthesis of novel ligands and catalysts used in asymmetric synthesis and cross-coupling reactions.
• Fluorine Chemistry Research: A valuable substrate for studying new fluorination methodologies and the physicochemical effects of gem-difluoro substitution in organic molecules.

Basic Information

Product Name	(1,1-Difluoro-2-Methylpropyl)-Benzene
CAS No.	1204295-83-9
Molecular Formula	C11H12F2
Molecular Weight	182.21 g/mol
Synonyms	α,α-Difluoro-2-methylpropylbenzene; Benzene, (1,1-difluoro-2-methylpropyl)-; 1,1-Difluoro-2-methyl-1-phenylpropane; (2-Methyl-1,1-difluoropropyl)benzene; 2-Methyl-1,1-difluoro-1-phenylpropane; (1,1-Difluoro-2-methylpropyl)benzene
EINECS	Contact for details

Quality Control

Our (1,1-Difluoro-2-Methylpropyl)-Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (GC/HPLC) and spectroscopy (NMR, IR), to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with relevant regulatory frameworks for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature is between 2°C and 8°C for long-term stability, although the material is typically stable at controlled room temperature for shorter periods. Keep container tightly sealed when not in use to prevent moisture absorption or contamination.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.