Description

2-Fluoro-6-(Pyrrolidin-1-Yl)Nicotinic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug candidates, especially kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to optimize lead compounds.
• Organic Synthesis Building Block: Serves as a versatile scaffold for constructing more complex nitrogen-containing heterocycles due to its reactive carboxylic acid and fluorinated pyridine core.
• Agrochemical Research: Potential application in the development of new herbicides and pesticides, leveraging its specific fluorinated structure.
• Material Science Precursor: Can be utilized in the synthesis of specialized ligands for catalysts or functional materials.

Basic Information

Product Name	2-Fluoro-6-(Pyrrolidin-1-Yl)Nicotinic Acid
CAS No.	1203499-55-1
Molecular Formula	C10H11FN2O2
Molecular Weight	210.21 g/mol
Synonyms	2-Fluoro-6-(pyrrolidin-1-yl)nicotinic acid; 6-(Pyrrolidin-1-yl)-2-fluoropyridine-3-carboxylic acid; 2-Fluoro-6-(1-pyrrolidinyl)-3-pyridinecarboxylic acid; 3-Pyridinecarboxylic acid, 2-fluoro-6-(1-pyrrolidinyl)-; 2-Fluoro-6-pyrrolidin-1-yl-nicotinic acid; 2-Fluoro-6-(pyrrolidin-1-yl)pyridine-3-carboxylic acid; 1203499-55-1
EINECS	Contact for details

Quality Control

Our 2-Fluoro-6-(Pyrrolidin-1-Yl)Nicotinic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.