Description

2-Fluoro-3-Iodo-6-(Pyrrolidin-1-Yl)Pyridine is a high-value, multi-functional heterocyclic building block designed for advanced synthetic chemistry. Its unique halogenated pyridine core, functionalized with a pyrrolidine substituent, makes it a critical intermediate for constructing complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing new active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Material Science: Acts as a building block for creating functional organic materials, such as ligands for metal-organic frameworks (MOFs) or organic semiconductors.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for studying biological pathways and target engagement.
• Cross-Coupling Reactions: The iodine and fluorine atoms make it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form complex biaryl systems.
• Medicinal Chemistry: Utilized in lead optimization and structure-activity relationship (SAR) studies to modulate the physicochemical and pharmacokinetic properties of drug candidates.

Basic Information

Product Name	2-Fluoro-3-Iodo-6-(Pyrrolidin-1-Yl)Pyridine
CAS No.	1203499-32-4
Molecular Formula	C9H10FIN2
Molecular Weight	292.09 g/mol
Synonyms	2-Fluoro-3-iodo-6-(1-pyrrolidinyl)pyridine; 6-(Pyrrolidin-1-yl)-2-fluoro-3-iodopyridine; 3-Iodo-2-fluoro-6-(pyrrolidin-1-yl)pyridine; 2-Fluoro-3-iodo-6-pyrrolidin-1-ylpyridine; Pyridine, 2-fluoro-3-iodo-6-(1-pyrrolidinyl)-; 1203499-32-4
EINECS	Contact for details

Quality Control

Our 2-Fluoro-3-Iodo-6-(Pyrrolidin-1-Yl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our commitment to reliable supply and documented quality supports your R&D and scale-up processes with confidence.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to protect from moisture and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.