Description

2-Fluoro-6-(Pyrrolidin-1-Yl)Nicotinaldehyde is a high-value fluorinated nicotinaldehyde derivative featuring a pyrrolidine substituent. This compound is a critical advanced pharmaceutical intermediate (API) used in the synthesis of complex bioactive molecules. It is primarily sought by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for developing new drug candidates and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides, leveraging its unique fluorinated heterocyclic structure.
• Ligand Synthesis: Serves as a precursor for creating complex ligands used in catalysis and material science applications.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Fine Chemical Synthesis: A versatile intermediate for constructing complex fluorinated organic molecules in custom synthesis and process development.

Basic Information

Product Name	2-Fluoro-6-(Pyrrolidin-1-Yl)Nicotinaldehyde
CAS No.	1203499-23-3
Molecular Formula	C10H11FN2O
Molecular Weight	194.21 g/mol
Synonyms	2-Fluoro-6-(1-pyrrolidinyl)-3-pyridinecarboxaldehyde; 6-(Pyrrolidin-1-yl)-2-fluoronicotinaldehyde; 3-Pyridinecarboxaldehyde, 2-fluoro-6-(1-pyrrolidinyl)-; 2-Fluoro-6-pyrrolidin-1-ylpyridine-3-carbaldehyde; 2-Fluoro-6-(pyrrolidin-1-yl)nicotinaldehyde; 1203499-23-3
EINECS	Contact for details

Quality Control

Our 2-Fluoro-6-(Pyrrolidin-1-Yl)Nicotinaldehyde is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and commercial synthesis. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles, supported by analytical methods including HPLC, GC, NMR, and mass spectrometry. Our quality system is designed to meet the stringent requirements of GMP environments for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.