Description

Pi3K Inhibitor CAS NO 1202884-94-3 is a potent and selective small molecule inhibitor of phosphoinositide 3-kinase (PI3K), a key enzyme in the PI3K/AKT/mTOR signaling pathway. This compound is critical for researchers and developers targeting dysregulated cell growth, proliferation, and survival mechanisms associated with various diseases. It is primarily utilized in pharmaceutical R&D for oncology, immunology, and metabolic disorder research, serving as a valuable tool compound for target validation and preclinical studies.

Application

• Biochemical Research: Used as a selective probe to study the role of PI3K signaling in cellular processes, including cell growth, metabolism, and survival.
• Oncology Drug Discovery: A key tool compound for screening and validating new therapeutic candidates targeting the PI3K pathway in various cancer models.
• Immunology Research: Applied in studies investigating the modulation of immune cell function and inflammatory responses through PI3K inhibition.
• Metabolic Disorder Studies: Utilized in research exploring the connection between PI3K signaling and conditions like diabetes and insulin resistance.
• Preclinical Development: Serves as a reference standard or active pharmaceutical ingredient (API) intermediate in the development of novel PI3K-targeted therapies.
• Academic Research: Widely used in university and institutional labs for fundamental biological research and high-impact publications.

Basic Information

Product Name	Pi3K Inhibitor CAS NO 1202884-94-3
CAS No.	1202884-94-3
Molecular Formula	C₂₄H₂₅N₇O₂
Molecular Weight	443.51 g/mol
Synonyms	GDC-0941; Pictilisib; 2-(1H-Indazol-4-yl)-6-[[4-(methylsulfonyl)piperazin-1-yl]methyl]-8-morpholin-4-yl-1,3-benzothiazin-4-one; GNE 0941; RG 7321; 2-(1H-Indazol-4-yl)-6-((4-(methylsulfonyl)piperazin-1-yl)methyl)-8-morpholino-4H-benzo[e][1,3]thiazin-4-one; PI3K inhibitor GDC-0941
EINECS	Contact for details

Quality Control

Our Pi3K Inhibitor is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and safety parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This product is hygroscopic (moisture-sensitive). Allow the vial to warm to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.