Description

4-Chloro-3-Ethoxybenzenesulfonyl Chloride (Saltdata: Free) is a high-purity, reactive sulfonyl chloride derivative used as a critical building block in advanced organic synthesis. Its value lies in its ability to introduce the sulfonamide functional group, a key moiety in the development of active pharmaceutical ingredients and specialty agrochemicals. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and material science industries who require a reliable and high-quality intermediate for constructing complex molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the sulfonamide group confers specific biological activity.
• Material Science Research: Serves as a monomer or cross-linking agent in the creation of specialized polymers and functional materials.
• Chemical Biology Probes: Employed in the design and synthesis of activity-based probes for studying enzyme function and protein interactions.
• Dye and Pigment Manufacturing: Acts as an intermediate in the production of sulfonated dyes and specialty colorants.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for use in multi-step synthetic routes for client-specific target molecules.

Basic Information

Product Name	4-Chloro-3-Ethoxybenzenesulfonyl Chloride (Saltdata: Free)
CAS No.	1202571-18-3
Molecular Formula	C8H8Cl2O3S
Molecular Weight	255.12 g/mol
Synonyms	1-Chloro-4-ethoxy-2-sulfonylchloride-benzene; 3-Ethoxy-4-chlorobenzenesulfonyl chloride; 4-Chloro-3-ethoxybenzenesulfonyl chloride; 4-Chloro-3-ethoxybenzene-1-sulfonyl chloride; Benzenesulfonyl chloride, 4-chloro-3-ethoxy-; 2-Chloro-5-ethoxybenzenesulfonyl chloride (isomer reference); 4-Chloro-3-ethoxy-phenylsulfonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 4-Chloro-3-Ethoxybenzenesulfonyl Chloride is manufactured and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, and NMR to ensure identity, purity, and consistency meet the exacting standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.