Description

(R)-1-(5-Fluoropyridin-2-Yl)Ethanamine Hydrochloride is a high-purity chiral amine building block essential for modern pharmaceutical research and development. Its core value lies in its role as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs), particularly for targeted therapies. This compound is primarily needed by pharmaceutical companies, contract research organizations (CROs), and academic research institutions focused on medicinal chemistry, process development, and the creation of novel drug candidates.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel Active Pharmaceutical Ingredients (APIs), especially in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new drug candidates.
• Process Chemistry Development: Serves as a starting material or intermediate in scaling up synthetic routes from laboratory to pilot plant scale.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or building block to introduce stereochemical complexity into target molecules.
• Chemical Biology Probes: Can be incorporated into molecular probes for studying biological targets and pathways.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	(R)-1-(5-Fluoropyridin-2-Yl)Ethanamine Hydrochloride
CAS No.	1202070-39-0
Molecular Formula	C7H10ClFN2
Molecular Weight	176.62 g/mol
Synonyms	(R)-1-(5-Fluoropyridin-2-yl)ethan-1-amine hydrochloride; (R)-1-(5-Fluoro-2-pyridinyl)ethylamine hydrochloride; (R)-α-Methyl-5-fluoropyridine-2-methanamine hydrochloride; (R)-5-Fluoro-2-(1-aminoethyl)pyridine hydrochloride; (R)-2-(1-Aminoethyl)-5-fluoropyridine hydrochloride; (R)-Enantiomer of 1-(5-Fluoropyridin-2-yl)ethanamine HCl
EINECS	Contact for details

Quality Control

Our (R)-1-(5-Fluoropyridin-2-Yl)Ethanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.