Description

Mps1/Ttk Inhibitor CAS NO 1202055-39-7 is a potent and selective small molecule inhibitor targeting the Mps1/TTK kinase, a critical regulator of the spindle assembly checkpoint in cell division. This compound is a valuable research tool for studying mitosis, chromosome instability, and cancer biology, offering insights into novel therapeutic strategies. It is primarily needed by pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on oncology, cell cycle biology, and high-throughput screening for anticancer drug discovery.

Application

• Biochemical and Cellular Research: Used as a selective probe to investigate the role of Mps1 kinase in mitotic checkpoint signaling and chromosome segregation.
• Oncology and Cancer Biology Studies: Essential for in vitro and in vivo studies exploring Mps1 inhibition as a potential therapeutic approach for various cancers.
• High-Throughput Screening (HTS): Serves as a reference compound or positive control in screening assays designed to discover new kinase inhibitors or modulators of cell division.
• Mechanism of Action (MoA) Studies: Employed to validate drug targets and understand the downstream effects of spindle assembly checkpoint disruption.
• Preclinical Drug Development: Used in pharmacokinetic, pharmacodynamic, and efficacy studies to support the development of novel anticancer agents.

Basic Information

Product Name	Mps1/Ttk Inhibitor
CAS No.	1202055-39-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	TTK Inhibitor; MPS1 Inhibitor; Mps1/TTK Kinase Inhibitor; 1202055-39-7; Monopolar spindle 1 kinase inhibitor; TTK protein kinase inhibitor; (Chemical name to be confirmed)
EINECS	Contact for details

Quality Control

Our Mps1/Ttk Inhibitor is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay results, and analytical methods is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccated conditions. This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and potency. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.