Description

1H-Indole-7-Carbonitrile, 6-Fluoro- is a high-value fluorinated indole derivative, a crucial building block in modern synthetic organic chemistry. Its molecular structure, featuring both a nitrile and a fluorine substituent on the indole core, makes it an essential intermediate for constructing complex molecules with targeted biological activity. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the fluorinated indole scaffold.
• Material Science: Serves as a precursor for advanced organic electronic materials and functional dyes due to its conjugated system.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and exploratory synthesis projects.
• Bioconjugation & Probe Synthesis: The reactive nitrile group allows for further functionalization, useful in creating biochemical probes and diagnostic agents.

Basic Information

Item	Detail
Product Name	1H-Indole-7-Carbonitrile, 6-Fluoro-
CAS No.	1201148-85-7
Molecular Formula	C9H5FN2
Molecular Weight	160.15 g/mol
Synonyms	6-Fluoro-1H-indole-7-carbonitrile; 6-Fluoro-7-cyanoindole; 6-Fluoroindole-7-carbonitrile; 7-Cyano-6-fluoroindole; 6-Fluoro-1H-indole-7-carbonitrile; 1H-Indole-7-carbonitrile, 6-fluoro-; 1201148-85-7
EINECS	Contact for details

Quality Control

Our 1H-Indole-7-Carbonitrile, 6-Fluoro- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 97.0% (Area Percent)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.