Description

6-(3-Isopropylureido)-4-(4-(Trifluoromethyl)Thiazol-2-Yl)Pyridin-3-Ylboronic Acid is a high-value, multifunctional boronic acid derivative designed for advanced synthetic chemistry. This compound is a critical building block in modern pharmaceutical and agrochemical research, enabling the construction of complex molecules through efficient cross-coupling reactions. It is primarily utilized by R&D chemists and process development scientists in the life sciences sector for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Research: Used to construct heterocyclic scaffolds for developing new pesticides and herbicides with enhanced efficacy.
• Material Science: Serves as a monomer or functionalization agent in the synthesis of advanced organic electronic materials and polymers.
• Chemical Biology: Employed as a probe or linker in bioconjugation and the development of chemical tools for biological target identification.
• Custom Synthesis: Supplied to contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects requiring specific boronic acid functionalities.

Basic Information

Product Name	6-(3-Isopropylureido)-4-(4-(Trifluoromethyl)Thiazol-2-Yl)Pyridin-3-Ylboronic Acid
CAS No.	1199362-17-8
Molecular Formula	C13H14BF3N4O3S
Molecular Weight	374.15 g/mol
Synonyms	4-(4-(Trifluoromethyl)-1,3-thiazol-2-yl)-6-[(3-methylbutan-2-yl)carbamoylamino]pyridin-3-ylboronic acid; 6-[(3-Methylbutan-2-yl)carbamoylamino]-4-[4-(trifluoromethyl)-1,3-thiazol-2-yl]pyridin-3-ylboronic acid; 6-(3-Isopropylureido)-4-(4-(trifluoromethyl)thiazol-2-yl)pyridin-3-ylboronic acid pinacol ester (common precursor); Boronic Acid, [6-[[(1-methylethyl)amino]carbonyl]amino]-4-[4-(trifluoromethyl)-2-thiazolyl]-3-pyridinyl]-; 1199362-17-8
EINECS	Contact for details

Quality Control

Our 6-(3-Isopropylureido)-4-(4-(Trifluoromethyl)Thiazol-2-Yl)Pyridin-3-Ylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., argon or nitrogen) due to its hygroscopic and moisture-sensitive nature. Allow the sealed container to reach room temperature before opening to prevent condensation and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥95%
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.