Description

7-Fluoro-Pyrido[1,2-A]Pyrimidin-4-One is a high-value fluorinated heterocyclic building block, specifically a pyridopyrimidinone derivative, essential for advanced pharmaceutical and agrochemical research. Its core value lies in its unique fused-ring structure and fluorine substitution, which are critical for modulating the biological activity, metabolic stability, and physicochemical properties of novel compounds. This intermediate is primarily needed by R&D chemists and process development scientists in the pharmaceutical industry for the synthesis of potential drug candidates, as well as in agrochemical research for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key scaffold in the research and development of new active pharmaceutical ingredients (APIs), particularly in oncology, CNS, and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used as a building block for creating novel herbicides, fungicides, and insecticides, where the fluorine atom enhances bioavailability and environmental stability.
• Chemical Biology & Probe Development: Serves as a core structure for designing fluorescent probes or enzyme inhibitors to study biological pathways.
• Material Science Research: Investigated as a precursor for organic electronic materials due to its conjugated π-system and potential for charge transport.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting drug discovery and development projects for global clients.

Basic Information

Product Name	7-Fluoro-Pyrido[1,2-A]Pyrimidin-4-One
CAS No.	1198413-01-2
Molecular Formula	C7H3FN2O
Molecular Weight	150.11 g/mol
Synonyms	7-Fluoropyrido[1,2-a]pyrimidin-4-one; 7-Fluoro-4H-pyrido[1,2-a]pyrimidin-4-one; 7-Fluoro-4-oxo-4H-pyrido[1,2-a]pyrimidine; 1198413-01-2; 7-Fluoro-pyrido[1,2-a]pyrimidin-4-one; 7-Fluoropyrido[1,2-a]pyrimidin-4(1H)-one; 7-Fluoro-1H-pyrido[1,2-a]pyrimidin-4-one
EINECS	Contact for details

Quality Control

Our 7-Fluoro-Pyrido[1,2-A]Pyrimidin-4-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to ensure maximum stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.