Description

C-Jun n-Terminal Kinase Peptide Inhibitor 1, D-Stereoisomer is a highly specific, cell-permeable peptide inhibitor designed to target the JNK signaling pathway. This compound is critical for research into cellular stress responses, apoptosis, and inflammatory diseases, offering a powerful tool for dissecting kinase-specific functions. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies engaged in drug discovery and molecular biology studies.

Application

• Biochemical Research: Used as a selective inhibitor to study the role of JNK1, JNK2, and JNK3 isoforms in signal transduction pathways.
• Drug Discovery & Development: Serves as a key pharmacological tool for validating JNK as a therapeutic target in preclinical models for conditions like neurodegeneration, cancer, and diabetes.
• Cell Biology Studies: Employed to investigate mechanisms of apoptosis, cellular stress response, and inflammatory cytokine production in various cell lines.
• Neuroscience Research: Applied in models of neuronal death and neuroinflammation to understand JNK's role in disorders such as Alzheimer's and Parkinson's disease.
• Inflammation & Immunology: Used to modulate T-cell activation and cytokine expression in studies of autoimmune and inflammatory diseases.
• High-Throughput Screening (HTS): Acts as a reference compound in assay development and screening campaigns for novel JNK inhibitors.

Basic Information

Product Name	C-Jun n-Terminal Kinase Peptide Inhibitor 1, D-Stereoisomer
CAS No.	1198367-70-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	JNK Inhibitor I, D-Stereoisomer; JNK Inhibitor Peptide, D-form; BI-78D3 (D-Stereoisomer); c-Jun N-terminal Kinase Inhibitor Peptide 1 (D-Isomer); JNKIP-1 (D-form); SP600125 Peptide Inhibitor Analog; TAT-JNK Inhibitor Peptide (D-isoform); D-JNKI-1
EINECS	Contact for details

Quality Control

Our C-Jun n-Terminal Kinase Peptide Inhibitor 1, D-Stereoisomer is manufactured under strict quality protocols suitable for research applications. Each batch is characterized and tested to ensure high purity and biological activity. Comprehensive Certificates of Analysis (COA) detailing purity, identity, and potency are provided to support your research integrity and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This material is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥95%
Water Content (KF)	≤5.0%
Biological Activity (IC50)	Contact for details
Solubility	Soluble in DMSO, Water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.