Description

(6-(Difluoromethoxy)Pyridin-3-Yl)Methanamine is a high-value pyridine derivative featuring a difluoromethoxy substituent, a structural motif of significant interest in modern synthetic chemistry. This compound serves as a critical pharmaceutical intermediate and building block for the development of novel active ingredients. It is primarily utilized by research institutions and industrial manufacturers in the agrochemical and pharmaceutical sectors, where its unique fluorinated structure is leveraged to modulate the biological activity, metabolic stability, and physicochemical properties of target molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the research and synthesis of new drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used as a building block for developing advanced crop protection agents, where the difluoromethoxy group can enhance bioactivity and environmental profile.
• Chemical Research & Development: Serves as a versatile precursor for introducing fluorinated motifs into more complex molecular architectures in academic and industrial R&D settings.
• Ligand and Catalyst Development: Potential use in creating specialized ligands for catalysis or as a component in material science research.
• Custom Synthesis Projects: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis under cGMP or non-GMP conditions.

Basic Information

Product Name	(6-(Difluoromethoxy)Pyridin-3-Yl)Methanamine
CAS No.	1198103-43-3
Molecular Formula	C7H8F2N2O
Molecular Weight	174.15 g/mol
Synonyms	1-(6-(Difluoromethoxy)pyridin-3-yl)methanamine; 3-Pyridinemethanamine, 6-(difluoromethoxy)-; (6-(Difluoromethoxy)-3-pyridinyl)methylamine; 6-(Difluoromethoxy)nicotinylamine; (6-(Difluoromethoxy)pyridin-3-yl)methylamine; 5-(Aminomethyl)-2-(difluoromethoxy)pyridine
EINECS	Contact for details

Quality Control

Our (6-(Difluoromethoxy)Pyridin-3-Yl)Methanamine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing key parameters such as assay, identity, and impurity profiles. For projects requiring regulatory support, we can supply material with full traceability and documentation aligned with cGMP and ISO standards upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider holding under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.